Estrogen Metabolism
The Estrogen Metabolism Assessment evaluates how estrogen is being processed in the body. A balance of anti and pro carcinogenic breakdown products of oestrogen are assessed and can shed light into many estrogen-dependent conditions and provides an important tool for monitoring dietary, lifestyle and hormone therapies.
Might I benefit from this test?
If you have a family history of hormonal cancers such as Breast and Uterine cancer or if you have a history of oestrogen dominance which can result in conditions such as PMS, fibroids and endometriosis then this test could be of value to you.
The potential impact of estrogen on a person’s health and well-being is enormous.
Estrogen can exert a strong influence in diverse conditions such as
- Breast cancer
- Prostate cancer
- Osteoporosis
- Heart disease
- Autoimmune disorders
Estrogen Metabolism
Estrogen metabolites provide valuable clinical information regarding cancer risk. Two significant metabolites (break down products) that can be accurately assessed are 16 alpha-hydroxyestrone
(16 alpha-OHE1) and 2-hydroxyestrone (2-OHE1).
• 16 alpha-OHE1 is a powerful metabolite that stimulates target tissues. Levels can rise in response to obesity, alcohol consumption, and toxic exposure. High levels of this potent metabolite are linked to increased risk and poorer prognosis in conditions linked to estrogen excess such as breast cancer and lupus.
2-OHE1 is a metabolite that binds weakly to cell receptors and may slow cell proliferation. Excessive levels of 2-OHE1 may increase the risk of osteoporosis in post-menopausal women with low estrogen.
The all Important Ratio
The ratio between 2-OHE1 and 16 alpha-OHE1 is the key to optimizing health.
Treatments that increase the 2:16 alpha-OHE1 ratio help to reduce the risk of estrogen dependent disease enabling correct dietary and supplemental choices and monitoring. The Estrogen Metabolism Assessment is designed for both premenopausal and postmenopausal women.
What is being measured
- Urine
- 2-OHE1, 16a-OHE1,
- 2-OHE1/16a-OHE1 ratio
Specimen Requirements
Urine—10ml first morning urine sample
Before Taking This Test
Premenstrual women: Collect the sample between days 19 and 25 of menstrual cycle
Women on HRT or oral contraceptives: Collect sample 8-10 hours after last dose
Urine: Patients should have normal kidney and urinary tract functions
Urine: Inform practitioner of diuretic use or excessive fluid intake
Schedule sample collection for Monday through Thursday
See instructions inside test kit for details
Turnaround Time - 25 Days
Buy Estrogen Metabolism Test - UK
Buy Estrogen Metabolism Plus Test
European Orders
Test kits can be sent out to Europe however there is an additional £7.00 fee added for administration and postage to you (added to the price below). You will be responsible for returning the test kit and this should arrive at the lab no later than 24 hours after the sample has been taken for delivery on monday, tuesday, wednesday or thursday only.
Buy Estrogen Metabolism Test - Europe
Buy Estrogen Metabolism Plus Test Europe
European Orders – Courier Delivery
Test kits can be sent out to Europe via our courier sevice however there is an additional fee added if you would like to use this service. You will be responsible for returning the test kit and this should arrive at the lab no later than 24 hours after the sample has been taken for delivery on monday, tuesday, wednesday or thursday only.
Buy Estrogen Metabolism Test - Courier Delivery Europe
Buy Estrogen Metabolism Plus Test Europe Courier Delivery
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