Cardiovascular Health Test
Nearly 50% of all heart attack victims have normal levels of traditional early warning markers for cardiovascular disease (CVD), including total cholesterol. For this reason, improved clinical tools are needed to identify patients with a predisposition to CVD who can benefit from timely, preventative intervention. The Comprehensive Cardiovascular Assessment measures state-of-the-art, independent markers that illuminate the clinical complexity of CVD.
Comprehensive Cardiovascular Assessment analyzes blood for lipid markers, ratios, and independent risk factors. Together, these markers provide a thorough assessment of cardiovascular health status, revealing the biochemical environment associated with inflammation, lipid deposits, endothelial dysfunction, clotting factors and other primary mechanisms underlying cardiovascular disease.
Homocysteine is an amino acid that functions as an intermediate in methionine metabolism. It can rise in response to nutritional deficiencies of B12, folate, B6, or betaine. High levels of homocysteine have been linked to damaged endothelium, increased platelet aggregation, and the formation of atherosclerotic lesions.
Lipoprotein(a) or Lp(a) is a marker strongly influenced by heredity. It has been cited for its causative role in atherothrombogenesis and its strong association with both coronary and peripheral cardiac events. Lp(a) promotes the deposit of fatty wastes and other debris in atherosclerotic lesions.
C-reactive protein (CRP) is an important independent marker for inflammation. High levels reflect overactivity of inflammatory cytokines linked to coagulation and vascular endothelium damage. Evidence suggests that previous infection with pathogens such as Chlamydia pneumoniae or Helicobacter pylori may act as an initiating trigger for this chronic inflammation. Elevated CRP has also been linked to a poorer long-term prognosis in individuals with a recent history of a cardiac event.
Fibrinogen plays a key role in arterial occlusion by promoting thrombus formation, endothelial injury and hyperviscosity.
Triglycerides may become elevated by diets containing excess amounts of saturated fats or carbohydrates. These elevations are implicated in the progression of both coronary and peripheral atherosclerosis.
Total, HDL and LDL cholesterol, and their ratios assess specific dynamics of lipid metabolism and their potential impact on CVD
A broad range of traditional and newer markers for cardiovascular disease are being mesured
- LDL size
- Insulin resistance score
- HDL -size
- LDL -size
- VLDL – size
Type of test
Blood. The sample needs to be centrifuged so please check that the place where you are having your blood taken is able to do this.
Before taking the test
An overnight fast of 12 hours – water only. Some medication such as statins, aspirin and warfarin may influence the results although testing whilst on medication or therapy can be done to monitor effectiveness.
Do not discontinue with any medication unless supervised by your doctor.